Modeling Hypoxia

Modeling Hypoxia

Myocardial ischemia is a pathological condition characterized by reduced oxygen supply (hypoxia) that can lead to cell death, arrhythmia, organ injury, and death. Ironically, returning hypoxic myocardium to normoxic levels exacerbates the pathology (collectively known as myocardial reperfusion injury). CDI’s cardiomyocytes are amenable to hypoxia induction, measurement of hypoxia-induced functional endpoints, and screening for cardioprotective agents.