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CDI/Molecular Devices Webinar: Using Stem Cell-derived Neurons in High Content Screening Assays for Drug Toxicity

June 27, 2012

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Induced pluripotent stem (iPS) cells are an ideal source of functional human cells that can be manufactured in large quantities to perform drug screening or test for toxic effects on specific target cell types. Human neurons derived from iPS cells, such as iCell® Neurons from Cellular Dynamics International, are very attractive for toxicity studies because they exhibit normal functionality and behavior of mature neurons.

During this webinar, we demonstrate the utility of several toxicity screening assays using iCell Neurons with the Molecular Devices ImageXpress® Micro High Content Imaging System. Experiments were run in 96 or 384 well plates to evaluate cell death, apoptosis, mitochondrial membrane damage, and impact on development of neuronal outgrowths over time.

View this webinar on demand.


June 27, 2012