News & Events

February 2013

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FEBRUARY 2013

Welcome to our monthly enewsletter, CDI Notebook, which will keep you abreast of the latest innovations using CDI’s iCell® and MyCell® products.

In this issue:
Conference News
iCell Screening Grant: Winners Announced
iCell Application Notes & Protocols
Published Research

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Conference News

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Japanese Safety Pharmacology Society Meeting (Feb 15 – 16, 2013). Join us at the following session to learn how human iPSC-derived cardiomyocytes recapitulate native physiology and are being used for toxicity screening:
Advances in Safety Pharmacology: Utilizing
Human Cardiomyocytes in Early Stage Safety Pharmacological Investigations

Blake Anson, PhD, Cellular Dynamics
Friday, Feb 15, 2013 | 4:30 – 5:50 pm

Society of Toxicology Annual Meeting & ToxExpo (Mar 10 – 14, 2013). Save the dates for the following events:

  • Application of Human iPSC-derived Hepatocytes Models for Toxicity Assessment
    Ed LeCluyse, PhD, The Hamner Institutes for Health Sciences
    Wednesday, Mar 13, 2013 | 1:00 – 2:00 pm
  • Customer Reception
    Tuesday, Mar 12, 2013 | 7:30 pm
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iCell Screening Grant: Winners Announced

Congratulations to the following group of researchers, who were awarded iCell cells to advance their phenotypic screening projects in the areas of coronary heart disease, stroke, autism, and tropical diseases:

iCell Cardiomyocytes

  • Kacey Caradonna, Harvard School of Public Health
  • Shawdee Eshghi, Silver Creek Pharmaceuticals

iCell Neurons

  • Karl Braunewell, Southern Research Institute
  • Jamie Freeman, University College London

iCell Endothelial Cells

  • Jason Hinman, UCLA

Grant Details>>

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iCell Application Notes & Protocols

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Modeling Cardiac Hypertrophy in iCell Cardiomyocytes. Introducing a suite of application protocols for inducing and quantifying cardiac hypertrophy with high content imaging, qRT-PCR, ELISA, or flow cytometry readouts.

Download>>

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Published Research

Varicella Zoster Virus Infection of Highly Pure Terminally Differentiated Human Neurons. This article describes the development of an in vitro model of varicella zoster virus (VZV) infection using iCell Neurons. Infection of these cells with VZV produces a nonproductive infection in the absence of apoptosis, thus enabling molecular analysis of VZV-neuronal relationship and studies of the mechanisms of VZV reactivation.

Yu X, Seitz S, Pointon T, Bowlin JL, Cohrs RJ, Stipan J, Haas J, Welllish M, Gilden D. (2012) J NeuroVirol. Published online ahead of print.

Article>>

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