Association of an Inherited Genetic Variant with Vincristine-related Peripheral Neuropathy in Children with Acute Lymphoblastic Leukemia. Discover how researchers identified genetic polymorphisms associated with chemotherapeutic-induced neuropathies in children with acute lymphoblastic leukemia (ALL) through a genome-wide association study (GWAS) and used iCell Neurons to corroborate their clinical findings.
Diouf B, Crews KR, et al. (2015) JAMA.
A Beating Heart Cell Model to Predict Cardiotoxicity: Effects of the Dietary Supplement Ingredients Higenamine, Phenylethylamine, Ephedrine and Caffeine. Access this manuscript to learn how investigators at the FDA are using iCell Cardiomyocytes for early determination of the effects that dietary supplements may have on cardiac behavior.
Calvert R, Vohra S, et al. (2015) Food Chem Toxicol.
Development and Characterization of a Scaffold-free 3D Spheroid Model of iPSC-derived Human Cardiomyocytes. Learn about the characterization and properties of iCell Cardiomyocytes in a recently developed, easy-to-use 3D model.
Beauchamp P, Moritz W, et al. (2015) Tissue Eng Part C: Methods.
Human iPSC-derived Hepatocyte-like Cells Support Plasmodium Liver-stage Infection In Vitro. Read how iCell Hepatocytes support research of malaria infection by P falciparum and P vivax parasites and show the applicability of these human iPS cells in drug discovery.
Ng S, Schwartz RE, et al. (2015) Stem Cell Reports.
Prediction of Drug-induced Liver Injury in Micropatterned Co-cultures Containing iPSC-derived Human Hepatocytes. Discover how iCell Hepatocytes demonstrate predictivity and sensitivity in assessing a panel of known hepatotoxins and safe compounds when cultured in a micropatterned co-culture model.
Ware BR, Berger DR, and Khetani SR. (2015) Toxicol Sci.