Products & Services

iCell® Cardiomyocytes2

Optimized for faster recovery and increased scientific throughput

iCell® Cardiomyocytes2  are an enhanced version of our extensively validated and predictive iCell Cardiomyocytes product. While they share most performance characteristics and boast advantages similar to those of the original iCell Cardiomyocytes product, iCell Cardiomyocytes2 have been optimized for faster recovery upon reanimation from cryopreservation. With iCell Cardiomyocytes2, you can increase scientific throughput while minimizing experimental handling and laboratory time.

  • Rapid recovery: Rebound quickly from cryopreservation to generate a mixture of spontaneously electrically active atrial-, nodal-, and ventricular-like myocytes
  • Electrophysiological response: Possess typical electrophysiological characteristics and exhibit expected electrophysiological and biochemical responses upon exposure to exogenous agents
  • Accelerated workflow: Provide a reliable and more rapidly implementable source of human cardiomyocytes for use in targeted drug discovery, toxicity testing, and other life science research applications

A Multitude of Applications

iCell Cardiomyocytes2 have demonstrated utility for electrophysiological and biochemical assays in toxicology, drug discovery, and basic life science research applications. Contact our Technical Support team for information on using iCell Cardiomyocytes2 in these types of studies.

  • Multielectrode array (MEA) recordings
  • Impedance-based measurements
Detecting Ion Channel Block

iCell Cardiomyocytes2 Provide an Accurate System for Detecting Ion Channel Block
Panels A and B show the expected increase in the field potential duration blocking IKr with E-4031. Panels C and D show the expected decrease in the field potential duration blocking the L-type calcium channels with NI. iCell Cardiomyocytes2 were exposed to the indicated compounds at the concentrations listed and the effects quantified ± SEM.



iCell Cardiomyocytes2 Capture Phenotypic Responses across Different Classes of Cardioactive Compounds
Modulating ion channel and GPCR activity alters the spontaneous contractile activity of iCell Cardiomyocytes2. Blocking IKr, ICa-L, and INa with E4031, NI, and INN and stimulating the β-adrenergic pathway with ISO produced the expected effects on the beat waveforms.


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    Catalog # Description Quantity Price
    R1017 iCell Cardiomyocytes2 Kit, 01434

    Each kit contains:

    • Cryopreserved iCell Cardiomyocytes2, 01434
    • 30 ml Plating Medium
    • 2 x 100 ml Maintenance Medium
    • User’s Guide
    >5 x 106
    Viable Cells/Vial
    Inquire About Pricing & Availability
    C1016 iCell Cardiomyocytes2, 01434

    Product contains:

    • Cryopreserved iCell Cardiomyocytes2, 01434
    • User’s Guide
    >5 x 106
    Viable Cells/Vial
    Inquire About Pricing & Availability
    M1003 iCell Cardiomyocytes Maintenance Medium

    Serum-based medium with pH indicator

    100 ml $125
    Inquire About Pricing & Availability
    R1151 iCell Cardiomyocytes Media Kit

    Each kit contains:

    • M1001 30ml iCell Cardiomyocytes Plating Medium
    • M1003 100ml iCell Cardiomyocytes Maintenance Medium
    1 Kit $375
    Inquire About Pricing & Availability