Products & Services

iCell® Hematopoietic
Progenitor Cells 2.0

A Reliable Source of Human Blood Cell Precursors

iCell Hematopoietic Progenitor Cells 2.0 are highly pure multipotent progenitor cells with the ability to differentiate into blood cell lineages. These cells can be consistently generated from human induced pluripotent stem cells in large-scale quantities, thereby overcoming the high variability and limited quantities associated with primary CD34++ cord blood or peripheral blood cells.

Advantages of iCell Hematopoietic Progenitor Cells 2.0

  • Reproducible results: High purity (>80% CD34+/CD43+) and rigorous quality control ensure the same performance with every batch.
  • Rapid results: Complete more studies in less time with ready-to-use iPSC-derived hematopoietic progenitor cells (HPCs).
  • Eliminate donor-to-donor variability:  iPSC-derived HPCs can be produced in essentially unlimited quantities from a single donor.

Applications

  • Targeted drug discovery
  • Hematotoxicity testing
  • Erythroid differentiation
  • Myeloid lineage differentiation
  • Infectious disease studies

Morphology

Morphology of iCell Hematopoietic Progenitor Cells 2.0

Figure 1: Morphology of iCell Hematopoietic Progenitor Cells 2.0
iCell Hematopoietic Progenitor Cells 2.0 display typical morphology as freely floating round cells.

Hematopoietic Progenitor Cell Markers

iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Express Hematopoietic Progenitor Cell Markers

Figure 2: iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Express Hematopoietic Progenitor Cell Markers
(A, B) Cells analyzed by flow cytometry at thaw are >90%+ for hematopoietic cell surface markers. (C) Percentage of cells expressing hematopoietic cell surface markers after thaw. Data shown as mean ±SEM; n=13.

Generation of Multiple Lineages

iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Generate Colonies of Multiple Lineages

Figure 3: iCell Hematopoietic Progenitor Cells 2.0 Reproducibly Generate Colonies of Multiple Lineages
iCell Hematopoietic Progenitor Cells 2.0 were plated in colony-forming unit (CFU) assays using a methylcellulose-based medium. (A) Representative images of colonies are shown. (B) CFU frequencies are shown, including erythroid (BFU-E), granulocyte/macrophage (CFU-M, CFU-G, CFU-GM) and mixed colonies (CFU-GEMM). Data shown as mean ±SEM; n=13.

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    Catalog # Description Quantity Price
    R1115 iCell Hematopoietic Progenitor Cells 2.0 Kit, 01279

    Each kit contains:

    • Cryopreserved iCell Hematopoietic Progenitor Cells 2.0, 01279
    • User’s Guide
    • Additional reagents required; see Quick Guide
    ≥1 x 106
    Viable Cells/Vial
    $1245
    Inquire About Pricing & Availability