Human Neurons & Glia = Access to the Brain!
The iCell® and MyCell® neural products portfolio, derived from human iPS cells, provides a relevant in vitro system to model and interrogate complex neurological processes and diseases.
From cortical iCell Neurons to cortical iCell Astrocytes to midbrain iCell DopaNeurons representing “typical” human biology to the specific genetic profiles or disease states of MyCell Products, we’ve got you covered!
These fully functional cells have demonstrated utility and value in driving new drug discovery approaches for disease modeling, phenotypic screening, target identification and validation, and much more.
More Data, More Publications, More Solutions
Compared to other commercially available iPS cell-derived neural cells, iCell and MyCell products boast the most published data and easy-to-implement application protocols.
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- SnapShot: Pathobiology of Alzheimer’s Disease Poster:
Alzheimer’s disease, the most common form of dementia, is characterized by an accumulation of amyloid-β-containing plaques and neurofibrillary tangles resulting in synaptic damage accompanied by neuronal loss. This poster highlights the key mechanisms that play a role are implicated in the progression of Alzheimer’s disease.
- Selected Bibliography of CDI Neuro-related Publications:
An increasing number of scientists are using CDI’s iCell and MyCell neuro-related products as a key part of their life science and drug discovery research as evidenced by this select list of peer-reviewed articles.
- iPSC-derived Motor Neurons Presentation:
Human iPS Cell-derived Motor Neurons for Modeling Neurological Disease
Human iPSC-derived motor neurons, at purities greater than 50%, from multiple donors were characterized and show electrophysiological functionality. These motor neurons provide a model system for studying this motor neuron diseases such as ALS and muscular dystrophies.