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Alzheimer’s disease, the most common form of dementia, is characterized by an accumulation of amyloid-β-containing plaques and neurofibrillary tangles resulting in synaptic damage accompanied by neuronal loss. This poster highlights the key mechanisms that play a role are implicated in the progression of Alzheimer’s disease.
An increasing number of scientists are using CDI’s iCell® and MyCell® neuro-related products as a key part of their life science and drug discovery research as evidenced by this select list of peer-reviewed articles.
Human iPSC-derived motor neurons, at purities greater than 50%, from multiple donors were characterized and show electrophysiological functionality. These motor neurons provide a model system for studying this motor neuron diseases such as ALS and muscular dystrophies.