Babiarz JE, Ravon M, Sridhar S, Ravindran P, Swanson B, Bitter H, Weiser T, Chiao E, Certa U, and Kolaja KL
Stem Cells Dev 21(11):1956-65
Publication Date: January 4, 2012
Product Type: iCell Cardiomyocytes
iCell Cardiomyocytes mRNA and miRNA transcriptomes were analyzed at various time-points during and post-differentiation and compared to primary cardiac tissue biopsied from human fetal, adult normal and hypertensive hearts.
This study demonstrated that iCell Cardiomyocytes exhibit developmental markers similar to native human cardiac tissue and maintain a stable cardiac cell phenotype for several months in culture. Data support the use of iCell Cardiomyocytes as a relevant human model system for both acute and chronic studies of cardiac cell function.