Fine M, Lu FM, Lin MJ, Moe O, Wang HR, and Hilgemann DW
Am J Physiol Cell Physiol 305(5):C481-91
Publication Date: June 26, 2013
Product Type: iCell Cardiomyocytes
iCell Cardiomyocytes were analyzed for cardiac ion transporter function. Data demonstrate that iCell Cardiomyocytes exhibit human adult-like expression of major cardiac ion transporters, are amenable to long-term molecular manipulation of individual transporter and regulatory proteins, and can be used for analysis of transporter and regulatory protein turnover.
Data support the use of iCell Cardiomyocytes for a wide range of new cellular and molecular experimentation that was previously not possible to elucidate the molecular function and regulation of ion transporters.