Publications

Summary:

High-throughput protein-based assays were developed with iCell Cardiomyocytes as a system to induce and ameliorate hypertrophy.

Impact:

This research demonstrates the practicality and utility of utilizing relevant native human biology in disease modeling and high-throughput screens for drug discovery.

Summary:

iCell Cardiomyocytes were able to predict QT prolongation and arrhythmia with greater accuracy than current in vitro models when challenged with a set of 118 public and proprietary compounds.

Impact:

This study demonstrates that iCell Cardiomyocytes provide improved proarrhythmia predictions on a higher throughput screening platform thus providing value-added data with fewer resources.