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February 2014

Gui L and Niklason LE

Vascular Tissue Engineering: Building Perfusable Vasculature for Implantation

Curr Opin Chem Eng 3:68-74

Publication Date: February 7, 2014

Product Type: iCell Endothelial Cells

Summary:

A review article describing the state of the art for vascular biology in generating perfusable tissues for therapeutic applications. The potential for iPSC-derived endothelial cells (ECs) in such applications is reported.

Impact:

iCell Endothelial Cells are currently commercially available as iCell Endothelial Cells (Cellular Dynamics International). As such, human iPSCs offer the advantages of providing a possibly unlimited number of autologous ECs to vascularize tissue engineered constructs for implantation.