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December 2007

Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, and Thomson JA

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Science 318(5858):1917-20

Publication Date: December 21, 2007

Product Type: CDI Technology


Showing that four factors (OCT4, SOX2, NANOG, and LIN28) are sufficient to reprogram human somatic cells to pluripotent stem cells that exhibit the essential characteristics of embryonic stem cells.