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October 2013

Sirenko O, Cromwell EF, Crittenden C, Wignall JA, Wright FA, and Rusyn I

Assessment of Beating Parameters in Human Induced Pluripotent Stem Cells Enables Quantitative In Vitro Screening for Cardiotoxicity

Toxicol Appl Pharmacol 273(3):500-07

Publication Date: October 1, 2013

Product Type: iCell Cardiomyocytes

Summary:

High-throughput protein-based assays were developed with iCell Cardiomyocytes as a system to induce and ameliorate hypertrophy.

Impact:

This research demonstrates the practicality and utility of utilizing relevant native human biology in disease modeling and high throughput screens for drug discovery.