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September 2011

Ma J, Guo L, Fiene SJ, Anson BD, Thomson JA, Kamp TJ, Kolaja KL, Swanson BJ, and January CT

High Purity Human-induced Pluripotent Stem Cell-derived Cardiomyocytes: Electrophysiological Properties of Action Potentials and Ionic Currents

Am J Physiol Heart Circ Physiol 301(5):H2006-17

Publication Date: September 2, 2011

Product Type: iCell Cardiomyocytes

Summary:

This comprehensive characterization study demonstrated that iCell Cardiomyocytes display cellular electrophysiological properties similar to native human cardiomyocytes.

Impact:

iCell Cardiomyocytes exhibit electrophysiological characteristics similar to native human cardiomyocytes and thus provide a relevant in vitro model for disease modeling, drug discovery, and toxicity testing.