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December 2012

Schweikart K, Guo L, Shuler Z, Abrams R, Chiao ET, Kolaja KL, and Davis M

The Effects of Jaspamide on Human Cardiomyocyte Function and Cardiac Ion Channel Activity

Toxicol In Vitro 27(20:745-51

Publication Date: December 20, 2012

Product Type: iCell Cardiomyocytes

Summary:

iCell Cardiomyocytes were used to demonstrate that the acute clinical toxicity of jaspamide, an anti-neoplastic agent, is due to drug-induced cardiotoxicity.

Impact:

iCell Cardiomyocytes were used to elucidate mechanisms of action of an anti-cancer drug associated with clinical toxicity.