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August 2012

Haythornthwaite A, Stoelzle S, Hasler A, Kiss A, Mosbacher J, George M, Brüggemann A, and Fertig N

Characterizing Human Ion Channels in Induced Pluripotent Stem Cell-derived Neurons

J Biomol Screen 17(9):1264-72

Publication Date: August 24, 2012

Product Type: iCell GABANeurons

Summary:

This characterization study demonstrated that iCell Neurons display cellular electrophysiological properties similar to native human neurons using manual and automated patch clamp recordings.

Impact:

iCell Neurons exhibit electrophysiological characteristics similar to native human neurons and thus provide a relevant in vitro model for disease modeling, drug discovery, and toxicity testing.