How can I monitor cardiotoxicity and cell health of cardiomyocytes?

How can I monitor cardiotoxicity and cell health of cardiomyocytes?


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Mioulane et al. (​2012) reviewed immunofluorescent monitoring options for examining cardiotoxicity. iCell® Cardiomyocytes have also been used to measure various cardiac cell health endpoints using a variety of platforms including:

  • Plate-based fluorescent and luminescent assays
  • Metabolism analysis (Seahorse Biosciences XF96)
  • High content analysis (Molecular Devices ImageXpress)
  • Impedance measurement (ACEA xCELLigence)

For more details about monitoring cardiotoxicity, see our Applications Webpage.

References:

  1. Mioulane et al. (​2012) Development of High Content Imaging Methods for Cell Death Detection in Human Pluripotent Stem Cell-derived Cardiomyocytes
  2. Cellular Dynamics Applications Webpage