How do you verify the metabolism of your cardiomyocytes?

How do you verify the metabolism of your cardiomyocytes?


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We have verified oxidative phosphorylation in iCell® Cardiomyocytes using an XF96 Extracellular Flux Analyzer (Seahorse Biosciences). In addition, Rana et al. (2012) tested for oxidative phosphorylation and glycolysis by measuring real-time oxygen consumption rates (OCRs) and extracellular acidification rates (ECARs) in iCell Cardiomyocytes using a Seahorse Biosciences instrument.

Reference:

  1. Rana et al. (2012) Characterization of Human-induced Pluripotent Stem Cell–derived Cardiomyocytes: Bioenergetics and Utilization in Safety Screening